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New Cancer Immunotherapy Aims Powerful T Cells Against Tumors

Deadly skin cancers in mice shrank in response to a new treatment that may complement other “immunotherapies” developed recently to boost the body’s own defenses against disease threats, according to a new study published by UC San Francisco researchers in the May 2014 edition of the Journal of Experimental Medicine. Read more

T cell repertoire changes predictive of anti-CTLA-4 cancer immunotherapy outcome

A recent study that investigates the effects of anti-CTLA-4 antibody on the number and types of T cells present in a patient’s blood. The results, which appear in the journal Science Translational Medicine, shed light on the mechanism of action of this type of cancer immunotherapy and suggest that immune repertoire sequencing could be used to predict which patients will have improved survival in response to treatment. Read more

Immunotherapy could help tackle tough liver cancer

Significant new data presented today at the International Liver Congress™ 2014 indicate that liver cancer (Hepatocellular Carcinoma (HCC)) may be treated by adoptive T-cell therapy. Read more

Immune cells may regulate blood stem cells

Researchers in Bern have discovered that, during a viral infection, immune cells control the blood stem cells in the bone marrow and therefore also the body’s own defences. The findings could allow for new forms of therapy, such as for bone marrow diseases like leukemia. Read more