First Chimeric antigen receptor T cell therapy approved in China

Yescarta (axicabtagene ciloleucel), a chimeric antigen receptor (CAR) T-cell therapy received approval from  China’s National Medical Products Administration on June 22, 2021, it is the first approved CAR T-cell therapy product in China.

The innovative CAR T-cell therapy from Fosun Kite Biotechnology is approved as a second-line treatment of adult patients with relapsed or refractory large B-cell lymphoma after two or more lines of systemic therapy, including diffuse large B-cell lymphoma (DLBCL) not otherwise specified, primary mediastinal large B-cell lymphoma, high grade B-cell lymphoma, and DLBCL arising from follicular lymphoma.

The product will soon be available in hospitals in China.

Apart from Yescarta, numbers of CAR T-cell therapy from international and domestic pharmaceutical giants are in clinical trials.

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