Cellular immunotherapy targets a common human cancer mutation

In a study of an immune therapy for colorectal cancer that involved a single patient, a team of researchers at the National Cancer Institute (NCI) identified a method for targeting the cancer-causing protein produced by a mutant form of the KRAS gene.

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Location of primary colon cancer predicts survival

Patients with colorectal cancer whose primary tumor is situated on the left side of the colon survive significantly longer than patients whose cancer starts on the right side, says new research to be presented at a meeting next month. Read more

Vitamin D ‘aids the immune system to fight colorectal cancer’

The study, published in Gut, contributes to a growing body of research by identifying an association between vitamin D and how the immune system responds to cancer cells among a large human population sample for the first time.

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Cheap anti-malaria drug shows promise against colorectal cancer

The researchers behind the study – from St George’s, University of London in the UK – write about their findings in the journal EBioMedicine. Read more

Promising new approach targets cancer protein to slow tumor growth

Sometimes a full-on assault isn’t the best approach when dealing with a powerful enemy. A more effective approach, in the long run, may be to target the support system replenishing the supplies that keep your foe strong and ready for battle. Read more

Better colon cancer screening with genetic tests

A non-invasive test that includes detection of the genetic abnormalities related to cancer could significantly improve the effectiveness of colon cancer screening, according to research published by a team of scientists including David Ransohoff, MD, professor of medicine at the UNC School of Medicine and UNC Lineberger Comprehensive Cancer Center member. The large-scale, cross-sectional study was published online today in The New England Journal of Medicine. Read more

Red and processed meat ‘increases colorectal cancer risk’

People with a common genetic variant who consume red or processed meat may increase their risk of colorectal cancer. This is according to a study presented at the annual American Society of Human Genetics 2013 meeting. Read more